First of all, make sure you have your color management settings in Draw in order, and that they work correctly with your RIP and printer(s).
When you open/import a PDF in Draw and the PDF has embedded color profiles, you can either choose to use them, ignore them (and use your defaults), or convert the colors to match your default color profiles.
I normally choose to ignore them, sometimes open twice (one ignore, one use/convert) to see how much it differs.
What you choose will affect what comes in but I can not say what is right for you.
RGB should import as RGB no matter what color mode your document is, since Draw can handle multiple models in the same document.
If the import part works as intended, the colors should be correct so far.
When it is time to Publish/Export to PDF again, it is absolutely crucial that you choose a preset that keeps as much of the original information as possible.
I suggest the "Editing" preset, it will export colors in their native color models, without converting from RGB or Pantone to CMYK for example.
It will also embed the color profiles but then it depends on your RIP settings whether they are used or ignored when printing.
The best thing to do, at least theoretically, should be to open/import the PDF and use the embedded profiles, do what needs to be done but without changing any colors, and then Publish to PDF again with the Editing preset with embedded profiles.
This should keep as much of the original information as possible.
Worth noting though, that importing/exporting files is always a bit risky, the filters are not perfect.