If you have an Edge/Edge 2 as part of your equation and do a lot of Spectratone or PANTONE work, I would strongly recommend moving to Omega 2. With the latest version currently available, 2.02, the Color ID software option is now included. To me (if you did this type of output) this would make the upgrade a sure hit and very justifiable from a cost standpoint.
Two features I really, really like about ArtPath 2.0: A) You can view the toolpaths in an animation and B) Support for grouped items coming into ArtPath (that was a big pain in the butt with some files in the past).
There a few other things here and there, but those two get the most work out from me. Both of these items and a few more could stand some additional attention, but resources being what they currently are at GSP, I’ll wait my turn in line.
As to a working “mixed version” environment; has been done in the past and still being done today. Some shops are simply refusing to move past GA 6.2. So yes, it’s doable. May be a bit of a pain having to remember to “save down” when some of the files will be used on the older software. But other then that, no problems.