Tony D had you change your VM.
This is an Edge I or II?
When it seems to "stop" do any of the buttons on the Edge itself do anything, or are they "frozen"? If this is the case I would point to "static". Lately it's been bad here in Connecticut.
I see NO reason to reboot the
computer, maybe restart the Edge, kill the job in GQMgr and resend it.
I'm also assuming that you printing the job and not letting it sit over night or for a long time for the next color, if so maybe (far fetched) but the port could be going to sleep and not waking up, again far fetched.
NOTE to ALL: GQmgr does NOT look for the security key. If you attempt to install a device from GQMgr then the setup module will need to find the key.